To give your hardest and strenuous daily routine a break long enough to refresh your abilities, you would probably need to spend extraordinary delightful time with your partner. The Weekend pill is a perfect choice for times like these. Lilly ICOS joint venture had launched Cialis, a potent sexual enhancer that has become the future of all such medications due to the longest duration of erection it claims to provide without harming the rest of the physiological processes of the body. Although a verified prescription drug, Cialis is an exceptionally potent enhancer of sexual stimulation for men.
Chemically, Cialis is composed of Tadalafil that block the action of PDE5 effectively to reduce cGMP degradation. cGMP degradation is a process causing fall in smooth muscle relaxation making the vessels less roomy for the blood inflow required for a longer and effective erection. Upon drug administration, the smooth muscle relaxant would not be degraded, thus its overall concentration would increase to cause rapid filling of corpus cavernosa with blood. However, sexual stimulation is a necessary evil meaning that the drug alone would not be able to bring about an erection unless appropriately stimulated physically.
The drug strongly interacts with nitrate containing drug to cause fatally harmful hypotension. Do not take antibiotics such as erythromycin and antifungal agents such along with Cialis. Do not take HIV medications along with the drug. Discuss with you physician about any renal, blood vascular, hepatic or cardiac impairments that you might have suffered from. Do not take the medication more than once in 24 hours. Do not take the medication you recently suffered from stroke or angina.
Take the drug half an hour prior to sexual interaction, once in 24 hours, the effects of which would last for as long as 36 straight hours. Available in 2.5mg, 5mg, 10mg and 20mg yellow colored almond shaped tablets, Cialis causes least possible side effects such as dizziness, hypotension, indigestion, nasal congestion, runny nose, headache, muscle ache, back ache and hearing problems. Visual side effects such as cyaniosis are substantially reduced as PDE6, and many other PDE’s apart from the targeted PDE5, is not affected by Cialis.
Cialis surpassed all other sexual enhances due to the fact that it is highly flexible regarding the food intake during sexual interaction. Providing the Longest erection time possible, Cialis does not interfere with body's other normal functions thus securing your sexual enhancement further. You could enjoy almost any meal while you are in the middle of a 36 hour long erection, although alcohol consumption is not advised as it might aggravate dizziness. Longer half life of Cialis of about 17.5 hours makes it last long enough in the blood that even after 36 hours of administration, 25% of the drug still remains in the blood.
If you are looking for medication that would make you experience the longest climaxes ever in highest frequency, Cialis is the perfect option to be considered. Surprisingly, our online pharmacy is availing its clients with high quality Cialis to be bought most affordable at your singe click.
CIALIS OF LILLY ICOS PHARM:
Bouts of sexual intercourse feed the love of a couple. Impotence is a disease which unfortunately jams the sexual pleasures in one’s sex life. To help millions of couples disturbed sexually by the influence of impotence, Lilly ICOS pharmaceuticals collaborated and after a lot of research and experimentation succeeded in introducing Cialis, a drug with amazing anti-impotence action. Cialis provides a gateway to the world of physical pleasures. The plus points of the drug include low side effects and food intake independence during drug action. Another remarkable feature of this drug is that it helps to promote erection for a time of about 26 hours once taken.
PROCESS OF ERECTION:
Penis is an organ covered with highly sensitive skin. The sensitive skin of penis encloses an erectile tissue called carpus cavarnosum. Carpus cavarnosum is called erectile tissue because it erects when the spaces inside it are filled with blood. Men unable to fill their erectile tissue with blood are deprived of erection. To fill cavities of cavarnosa cavarnosum with blood, there must be sufficient amount of cGMP generation in the blood vessels when sexual stimulation is provided to the man. Men having insufficient amount of cGMP cannot dilate their penile vessels. Dilation is necessary for the escape of blood out of the penile vessels. Cialis arrests the action of phosphodiesterase, an enzyme attributed to the breakdown of cGMP into GMP. Inhibition of cGMP destruction leads to increased concentration of cGMP, which then performs its vasodilatory role optimally, hence resulting in potent satisfactory erection.
SCHDULE AND DOSE FORMS:
Physicians prescribe the medication to be taken half an hour before sexual interaction which is the time required for the drug to be properly absorbed and activated inside the body. After, you have begun with the sexual stimulation; the erectile accelerating effect of the drug would last for the longer duration of 36 hours as compared to conventional sexual enhancements other than this drug. The available dosages of the drug are 5mg, 10mg and 20mg tablets to be ingested orally for not more than once in 24 hours time. Doing otherwise could dangerously lower your blood pressure which might precipitate into circulatory shock. Moreover, other vasodilators, nitrate containing medications are strong contraindicated with the drug as they might act synergistically with the drug to lower the blood pressure.
SPECIAL FEATURES OF CIALIS:
Of course, there are important factors behind the fast growing popularity of Cialis. Some of these factors are food insensitivity, minimized side effects and longer duration. One could enjoy any sort of tasty foods and spice up his love sessions that could be as long as 36 hours without having to worry about the side effects which is not the case with other conventional sexual medications. The drug specifically targets the PDE-5 of all the PDE enzymes found in the body and abstains from manifesting and additional, or even harmful, side effects.
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A well known medicine for the treatment of man impotence is Cialis. Cialis is also called Tadalafil. It is the generic name of Cialis and mostly used by the chemists and professional doctors.
FUNCTIONAL ANATOMY OF TESTIS
The testes are ovoid or walnut shaped bodies having the organization of compound tubular gland. Both the testes are located in the sac like structure called scrotum and are suspended.
■ COVERINGS OF TESTIS
Each testis is enclosed by three coverings.
1. Tunica vasculosa - the inner most covering made up of connective tissue; it is rich in blood vessels
2. Tunica albuginea - the dense middle fibrous capsule
3. Tunica vaginalis - the outermost closed cleft like covering which is formed by visceral and parietal layers. Both the layers are constituted by mesothelial cells.
All the three layers cover the anterior and lateral surfaces of testis and the posterior surface is covered byJunica-albuginoa only. The visceral layer of tunica vaginalis adheres to tunica albuginea as a smooth glistening membrane. Both these layers slide on one another and allow free movement of testis. The parietal layer lines the inner surface of the scrotum.
The tunica albuginea on the posterior surface of testis is thickened to form the mediastinum testis. From this, the connective tissue septa called septula testis.radiate into testis and bind with tunica albuginea at various points. By this, the interior of testis is divided into a number of pyramidal lobules, with bases directed towards the periphery and the apices at the mediastinum.
The septula do not form complete partition. Because of this, the lobules of testis anastomose with one another at many places.
■ PARENCHYMA OF TESTIS
Each lobule of testis contains 1-4 coiled tubules known as the seminiferous tubules. The seminiferous tubules are surrounded and supported by interlobular connective tissue. The length of each seminiferous tubule is between 30 and 70 cm. The diameter of the tubules is between 150 and 300 u. The seminiferous tubules do not end bluntly but, form single, double or triple arches. The limbs of an arch are not in the same lobule.
Towards the apex of each lobule, the convoluted tubules unite with a narrow straight tubule. The straight tubules from all the lobules pass into mediastinum. There, the straight tubules join and form a network of thin walled channels called the rete testis.
From rete testis, 8 to 15 tubules called vas efferens arise. Vas efferens form the head of epididymis and then converge to form duct of epididymis.
The duct of epididymis is an enormously convoluted tubule with a length of about 4 meters. It begins at head, where it receives vas efferens. At the caudal pole of testis, it turns sharply upon itself and passes as vas deferens without any definite demarcation. In between the semini¬ferous tubules in the testis, there are some hormone secreting cells called interstitial cells of Leydig.
■ SEMINIFEROUS TUBULE
The wall of the seminiferous tubule is formed by three layers:
1. The outer capsule or tunica propria formed by fibro elastic connective tissue
2. A thin homogeneous basement membrane
3. The complex stratified epithelium which consists of two types of cells:
I. Germ cells or spermatogenic cells
II. Supporting cells called cells of Sertoli.
The germ cells lie in between the Sertoli cells and are arranged in an orderly manner in 4 to 8 layers. These cells occupy the spaces between basement membrane and lumen of seminiferous tubules.
In children, the testis is not fully developed. Therefore, only the primitive germ cells called spermatogonia are present. With onset of sexual maturity, the spermatogenic cells are represented in all stages of differentiation.